Detalhe da pesquisa
1.
Fruquintinib versus placebo in patients with refractory metastatic colorectal cancer (FRESCO-2): an international, multicentre, randomised, double-blind, phase 3 study.
Lancet
; 402(10395): 41-53, 2023 07 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-37331369
2.
Influenza A virus polymerase acidic protein E23G/K substitutions weaken key baloxavir drug-binding contacts with minimal impact on replication and transmission.
PLoS Pathog
; 18(7): e1010698, 2022 07.
Artigo
em Inglês
| MEDLINE | ID: mdl-35830486
3.
The AI-driven Drug Design (AIDD) platform: an interactive multi-parameter optimization system integrating molecular evolution with physiologically based pharmacokinetic simulations.
J Comput Aided Mol Des
; 38(1): 14, 2024 Mar 19.
Artigo
em Inglês
| MEDLINE | ID: mdl-38499823
4.
Primary and secondary care service use and costs associated with frailty in an ageing population: longitudinal analysis of an English primary care cohort of adults aged 50 and over, 2006-2017.
Age Ageing
; 53(2)2024 Feb 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-38337044
5.
Antiviral Susceptibility of Highly Pathogenic Avian Influenza A(H5N1) Viruses Circulating Globally in 2022-2023.
J Infect Dis
; 2023 Sep 28.
Artigo
em Inglês
| MEDLINE | ID: mdl-37770028
6.
A randomised controlled trial of long NY-ESO-1 peptide-pulsed autologous dendritic cells with or without alpha-galactosylceramide in high-risk melanoma.
Cancer Immunol Immunother
; 72(7): 2267-2282, 2023 Jul.
Artigo
em Inglês
| MEDLINE | ID: mdl-36881133
7.
Swine H1N1 Influenza Virus Variants with Enhanced Polymerase Activity and HA Stability Promote Airborne Transmission in Ferrets.
J Virol
; 96(7): e0010022, 2022 04 13.
Artigo
em Inglês
| MEDLINE | ID: mdl-35254104
8.
Imaging of pediatric calvarial and skull base tumors: A COG Diagnostic Imaging Committee/SPR Oncology Committee/ASPNR White Paper.
Pediatr Blood Cancer
; 70 Suppl 4: e30165, 2023 06.
Artigo
em Inglês
| MEDLINE | ID: mdl-36565281
9.
Does the Thymus Index Predict COVID-19 Severity?
J Comput Assist Tomogr
; 47(2): 236-243, 2023.
Artigo
em Inglês
| MEDLINE | ID: mdl-36728781
10.
Influenza A and B viruses with reduced baloxavir susceptibility display attenuated in vitro fitness but retain ferret transmissibility.
Proc Natl Acad Sci U S A
; 117(15): 8593-8601, 2020 04 14.
Artigo
em Inglês
| MEDLINE | ID: mdl-32217734
11.
The Role of Systemic Therapy in Resectable Colorectal Liver Metastases: Systematic Review and Network Meta-Analysis.
Oncologist
; 27(12): 1034-1040, 2022 12 09.
Artigo
em Inglês
| MEDLINE | ID: mdl-36239399
12.
Comparative accuracy and cost-effectiveness of dynamic contrast-enhanced CT and positron emission tomography in the characterisation of solitary pulmonary nodules.
Thorax
; 77(10): 988-996, 2022 10.
Artigo
em Inglês
| MEDLINE | ID: mdl-34887348
13.
Germline Cancer Susceptibility Gene Testing in Unselected Patients With Colorectal Adenocarcinoma: A Multicenter Prospective Study.
Clin Gastroenterol Hepatol
; 20(3): e508-e528, 2022 03.
Artigo
em Inglês
| MEDLINE | ID: mdl-33857637
14.
Shifting stoichiometry: Long-term trends in stream-dissolved organic matter reveal altered C:N ratios due to history of atmospheric acid deposition.
Glob Chang Biol
; 28(1): 98-114, 2022 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-34706120
15.
Amplifying the Student Voice: Medical Student Perceptions of AΩA.
J Gen Intern Med
; 2022 Jun 28.
Artigo
em Inglês
| MEDLINE | ID: mdl-35764758
16.
Circulating tumor DNA (ctDNA) to evaluate minimal residual disease (MRD), treatment response, and posttreatment prognosis in pancreatic adenocarcinoma.
Pancreatology
; 22(6): 741-748, 2022 Sep.
Artigo
em Inglês
| MEDLINE | ID: mdl-35725696
17.
Patient, clinician and manager experience of the accelerated implementation of virtual consultations following COVID-19: A qualitative study of preferences in a tertiary orthopaedic rehabilitation setting.
Health Expect
; 25(2): 775-790, 2022 04.
Artigo
em Inglês
| MEDLINE | ID: mdl-35014124
18.
The role of circulating tumor DNA in evaluating minimal residual disease in luminal gastrointestinal malignancies.
Clin Adv Hematol Oncol
; 20(7): 444-455, 2022 Jul.
Artigo
em Inglês
| MEDLINE | ID: mdl-35802877
19.
Recurrent Wnt medulloblastoma treated with marrow-ablative chemotherapy and autologous hematopoietic progenitor cell rescue: a dual case report and review of the literature.
Childs Nerv Syst
; 38(2): 465-472, 2022 02.
Artigo
em Inglês
| MEDLINE | ID: mdl-33948723
20.
Baloxavir Treatment Delays Influenza B Virus Transmission in Ferrets and Results in Limited Generation of Drug-Resistant Variants.
Antimicrob Agents Chemother
; 65(11): e0113721, 2021 10 18.
Artigo
em Inglês
| MEDLINE | ID: mdl-34424039